Meso Pigment Reduce — targeted depigmentation

MESO PIGMENT REDUCE is an intense, effective and innovative treatment for hyperpigmentation, melasma, sun damage, age spots, discolorations and dark circles. It helps reduce and prevent spots on the face, body and hands.

Melanogenesis and unhealthy skin color

Skin color results from multiple pigments: haemoglobin in red blood cells and carotene in adipocytes. Most decisive is melanin, produced by melanocytes in the epidermis, which regulates skin color via complex mechanisms.

Unhealthy coloration is usually due to excess melanin or deposition of other pigments in the epidermis — locally or more widespread. Discolorations vary in origin and depth.
 

How to use

Apply the product twice daily directly to the area. Effects are typically visible after the first applications.
 

Key ingredients

Glabridin — isoflavonoid from Glycyrrhiza glabra root. In vitro/in vivo shows antioxidant, anti‑inflammatory, neuroprotective, antiteratogenic, antibacterial and depigmenting activity with topical use. The depigmenting effect is multifunctional and addresses several causes of unhealthy coloration.

Vitamin C (ascorbic acid) — reduces melanin production by reducing o‑DOPAchinone to DOPA and interrupting the oxidation process that forms melanin. The more stable profile enhances overall effect.

Arbutin — natural glucoside of hydroquinone (hydroquinone‑β‑D‑glucopyranoside). Studies on human melanocytes indicate a mechanism different from synthesis/enzyme expression. Clinical use without hydroquinone‑typical side effects.

Kojic acid — inhibits tyrosinase via copper chelation at the active site. Clinically documented depigmenting effect and safety. Inhibits MITF‑related transcription and α‑MSH‑stimulated melanogenesis.

Azelaic acid — depigmenting via competitive tyrosinase inhibition.

Niacinamide — biologically active amide of vitamin B3. Together with sun protection, clarity can improve more than with sun protection alone.

Vitamin A (retinoic acid) — depigmenting via increased keratinocyte turnover (epidermal pigment loss) and indirect cytotoxic effect on melanocytes by inhibiting detox pathways.

Pueraria (Kudzu) — root/flower used traditionally; multiple studies show inhibition of melanogenesis (confirmed by Fontana‑Masson staining).

Brassica napus seed extract — antioxidant‑rich; in vitro/in vivo shows reduction of discoloration and a more even tone.

The treatment addresses

Fast brightening effect

• Reduces the visibility of uneven skin tone and pigment build‑up by effectively inhibiting melanin synthesis. Delivers a more even, light‑reflecting skin surface after just a few sessions.

Hyperpigmentation

• Targets both superficial and deeper pigment changes, including sun damage and post‑inflammatory hyperpigmentation. Works by regulating melanocyte activity and improving the skin’s natural regeneration.

Age spots (lentigines)

• Reduces age‑related dark spots through a combination of brightening actives and cell‑renewing mechanisms. The result is a more even tone with reduced contrast between the spot and surrounding skin.

Dark circles under the eyes

• Acts on both vascular and pigmented dark circles. Improves microcirculation, reduces melanin build‑up and strengthens periorbital skin structure for a fresher, more rested look.

Treatment areas

Face:

• Treats pigmentary disorders such as melasma, sun damage and dark circles.
• Evens out skin tone and lightens dark spots for a more uniform, radiant complexion.
• Supports anti‑age benefits by stimulating natural cell renewal and improving firmness and elasticity.

Body:

• Suited to areas exposed to sun damage and uneven pigmentation, e.g., neck, décolletage, arms and legs.
• Reduces and helps prevent dark spots for a smoother, more even tone.
• Moisturising and nourishing ingredients strengthen the barrier, supporting smoother, more youthful‑looking skin.

Hands:

• Effective against age spots, uneven pigmentation and dryness on the hands.
• Helps brighten and even the appearance of the hands for a younger, well‑groomed look.

Anti‑age benefits:

• Cell‑renewing, moisturising and nourishing ingredients help reduce the appearance of fine lines and wrinkles.
• Antioxidants and collagen‑stimulating agents support elasticity and firmness, resulting in a more youthful skin structure.

Effect on dark spots:

• Meso Pigment Reduce contains brightening, melanin‑regulating actives that target and help prevent hyperpigmentation, melasma, age spots and dark circles.
• With continued use, the complexion appears clearer, more even and free from visible pigment changes.